文章来源:福州博润白癜风诊疗中心健康咨询热线:0535-4088888
以下英语文献由百度翻译:
热门问题:有治疗白癜风的方法吗?Is there any cure for vitiligo?
热门回答:
Originally Answered: What is the best vitiligo treatment start?
初的回答是:白癜风的治疗方法是什么?
In vitiligo, pigment cells (melanocytes) are destroyed. The condition is present in about 1% of the population, and may be associated with other autoimmune disorders, such as autoimmune thyroid disease, pernicious anemia, diabetes mellitus, and Addison disease.
在白癜风中,色素细胞(黑素细胞)被破坏。约1%的人群存在这种疾病,可能与其他自身免疫性疾病有关,如自身免疫性甲状腺疾病、恶性贫血、糖尿病和Addison病。
Therapy for vitiligo is long and tedious, and the patient must be strongly motivated. If <20% of the skin is involved (most cases), topical tacrolimus 0.1% twice daily is the first-line therapy. A superpotent corticosteroid may also be used, but local skin atrophy from prolonged use may ensue. With 20–25% involvement, narrowband UVB or oral PUVA is the best option. Severe phototoxic response (sunburn) may occur with PUVA. The face and upper chest respond best, and the fingertips and the genital areas do not respond as well to treatment. Years of treatment may be required. There is some emerging evidence that JAK inhibitors (tofactinib) may have a role in the treatment of vitiligo.
白癜风的治疗是漫长而乏味的,患者必须有强烈的动机。如果<20%的皮肤受累(大多数病例),每天两次外用0.1%他克莫司为一线治疗。也可以使用皮质类固醇,但长期使用可能导致局部皮肤萎缩。有20-25%的患者参与,窄带UVB或口服PUVA是选择。PUVA可能出现严重的光毒性反应(晒伤)。面部和上胸部对治疗反应,指尖和区域对治疗反应不好。可能需要几年的治疗。有一些新的证据表明JAK抑制剂(tofactinib)可能在白癜风的治疗中发挥作用。
Papadakis, Maxine A., et al. Current Medical Diagnosis & Treatment 2019. McGraw-Hill Education, 2019. p. 167.
Papadakis,Maxine A.等人,《2019年当前医学诊断与治疗》。麦格劳·希尔教育,2019年。P167